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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRP12 All Species: 16.97
Human Site: T245 Identified Species: 37.33
UniProt: Q5JTH9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JTH9 NP_001138586.1 1297 143702 T245 Y H G L L S F T V H P K P K I
Chimpanzee Pan troglodytes XP_001161750 1295 143474 T245 Y H G L L S F T V H P K P K I
Rhesus Macaque Macaca mulatta XP_001102543 1293 142811 K245 A Q D S V H M K A L I R K A A
Dog Lupus familis XP_850930 1324 146892 T269 Y H G L L S F T V H P K P K I
Cat Felis silvestris
Mouse Mus musculus Q6P5B0 1295 143113 T245 Y H G L L S F T V H A K P K I
Rat Rattus norvegicus XP_001054805 1232 136504 L245 S R E A T T T L H M L T L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKD5 1294 144034 C247 Y H G L L S F C V H T K P K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001025447 1283 142914 K245 L S F T V H S K P K V R K A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYA7 1384 153539 S267 F D A I L A F S I H S Q P K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_497319 1334 147629 A245 L V S V A A L A A H D K P W V
Sea Urchin Strong. purpuratus XP_792353 1431 157647 N305 Q I Y H G I L N Y T V H S K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 92.2 90.1 N.A. 90.7 85.4 N.A. N.A. 71.1 N.A. 61.8 N.A. 30.2 N.A. 26.6 44.3
Protein Similarity: 100 99.6 94.5 93.9 N.A. 94.9 90.2 N.A. N.A. 84.5 N.A. 79.7 N.A. 50.2 N.A. 45.5 64.7
P-Site Identity: 100 100 0 100 N.A. 93.3 0 N.A. N.A. 80 N.A. 0 N.A. 40 N.A. 20 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 6.6 N.A. N.A. 86.6 N.A. 13.3 N.A. 80 N.A. 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 10 19 0 10 19 0 10 0 0 19 19 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 10 0 0 0 55 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 46 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 46 0 10 0 19 0 0 10 64 0 10 0 0 0 % H
% Ile: 0 10 0 10 0 10 0 0 10 0 10 0 0 0 46 % I
% Lys: 0 0 0 0 0 0 0 19 0 10 0 55 19 64 10 % K
% Leu: 19 0 0 46 55 0 19 10 0 10 10 0 10 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 28 0 64 0 10 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 19 0 0 0 % R
% Ser: 10 10 10 10 0 46 10 10 0 0 10 0 10 0 0 % S
% Thr: 0 0 0 10 10 10 10 37 0 10 10 10 0 0 0 % T
% Val: 0 10 0 10 19 0 0 0 46 0 19 0 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 46 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _